ALDOSTERONE EXCRETION IN VIRILIZING ADRENAL HYPERPLASIA *

Aldosterone Excretion in Virilizing Adrenal

Sodium depletion with concomitant dehydration occurs as a complicating factor in approximately one-third of patients with virilizing adrenal hyperplasia (1). A number of writers have discussed certain differences between the electrolyte disturbance occurring in this syndrome and that of Addison's disease (2-5) and several hypotheses have been offered to explain the sodium loss and potassium ret...

Birthweight in congenital virilizing adrenal hyperplasia.

The deficiency of C-21-hydroxylation in adrenocorticosteroid synthesis is the commonest cause of congenital virilizing adrenal hyperplasia (CVAH). Abnormal secretory activity in CVAH begins about the third month of gestation before the differentiation of external genitalia (Bierich, 1963). The masculinization of the female external genitalia noted at birth in almost all cases is thought to resu...

Incidence of salt-losing form of congenital virilizing adrenal hyperplasia.

Isdale, J. M. (1970). Interstitial emphysema of the stomach. British journal of Radiology, 43, 146. Sisk, P. B. (1961). Gas in the portal venous system. Radiology, 77, 103. Susman, N., and Senturia, H. R. (1960). Gas embolization of the portal venous system. American j'ournal of Roentgenology, 83, 847. Touloukian, R. J., Berdon, W. E., Amoury, R. A., and Santulli, T. V. (1967). Surgical experie...

Urinary steroids in fifteen cases of congenital virilizing adrenal hyperplasia.

Since it was shown by Wilkins et al. (1950) that high output of urinary 17-ketosteroids in cases of congenital virilizing adrenal hyperplasia was suppressed by administration of glucocorticoids, the syndrome has been considered to be due to a deficiency in the enzymatic processes necessary for biosynthesis of cortisol. The most common type of the cases shows disturbances in changing 17ƒ¿hydroxy...

Aldosterone excretion in normal children and in children with adrenal hyperplasia.